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Treatment of Active Tuberculosis Disease

Public Health, Policy & Planning

San Mateo County follows treatment recommendations for active tuberculosis disease set forth by the California Tuberculosis Controller’s Association (CTCA) adapted from the Centers for Disease Control (CDC). The recommendations by the CTCA differ slightly from the CDC’s guidelines.

We have also highlighted below important matters for managing a patient with active TB disease in San Mateo County.

Treatment Monitoring

For patients with drug susceptible tuberculosis, San Mateo County follows a specific schedule of monitoring. This allows for appropriate assessment of clinical improvement. While all components of monitoring are essential, documented culture conversion after eight weeks of treatment is of particular importance to patient treatment.

Directly Observed Therapy (DOT)

San Mateo County uses DOT as a tool to support patients through a lengthy course of treatment, improve tuberculosis treatment adherence and minimize adverse outcomes. All patients with pulmonary TB or drug resistant TB, as well as patients on intermittent regimens, should be on DOT.  DOT is also strongly recommended for others at high risk for serious outcomes or poor adherence.

HIV Testing

Since HIV co-infection is a significant risk factor for progression to active tuberculosis disease, and also alters medical management of tuberculosis, San Mateo County follow the California Department of Public Health (CDPH) and Centers for Disease Control (CDC) recommendation that all patients with suspected or confirmed tuberculosis be tested for HIV.

Do you have questions?

We are available for consultation at 650-573-2346.